StratCare-2
Evaluating the clinical and cost effectiveness of stratified care for depression.
Background
Over a million NHS patients access psychological treatments in primary care each year, which are currently delivered in a stepped care model. This model does not always work, as recovery rates for depression treatments are approximately 50%. An alternative way to organise psychological treatments is using a stratified care model, based on principles of precision medicine, where patients are matched to the most appropriate treatment for their needs.
StratCare is a web-based computerised app that guides therapists on how to assess new patients and integrates seamlessly with the Talking Therapies assessment process. It asks a few questions about patient symptoms, personality and background, to make a recommendation about which treatment might be most effective for that person - either starting with brief therapy or with intensive therapy. The patient can discuss with their therapist and decide whether to accept the recommendation. StratCare uses a stratified care model, where patients are matched to the most appropriate treatment for their needs.
The StratCare-2 Trial
StratCare-2 builds on an earlier trial which found that ‘StratCare’ can help more people to recover from depression compared to the usual stepped care model. One group of patients receive a treatment recommendation made using the StratCare app. The treatment recommendation for the other group is made using usual shared decision making
StratCare-2 will evaluate the longer-term clinical- and cost-effectiveness of AI-driven stratified care versus usual stepped care for people with depression, by following up patients to 18 months after joining the trial. Eligible patients will be attending an assessment for Talking Therapies, be 18 or over, be suitable for treatment within the service, and have case level depression symptoms (PHQ-9≥10).
Project leadership group
Name | Role | Organisation |
|---|---|---|
Prof. Jaime Delgadillo | Chief Investigator | СŷÊÓƵ |
Prof. Michael Barkham | Joint Lead Applicant, Professor of Clinical Psychology | СŷÊÓƵ |
Prof. Cindy Cooper | CTRU Oversight | СŷÊÓƵ |
Katie Biggs | CTRU Joint Lead | СŷÊÓƵ |
Cara Mooney | CTRU Support | СŷÊÓƵ |
Prof. Stephen Walters | CTRU Senior Statistician | СŷÊÓƵ |
Peter Bower | Professor of Health Services Research | СŷÊÓƵ |
Isabelle Wilson | Statistician | СŷÊÓƵ |
Jon Woodward | Trial Manager | СŷÊÓƵ |
Joe Spencer | Research Assistant | СŷÊÓƵ |
Tom Hutton | Trial Support Officer | СŷÊÓƵ |
Tony Whiting | PPI Representative | N/A |
Simon Gilbody | Professor of Psychological Medicine & Psychiatric Epidemiology | The СŷÊÓƵ of Manchester |
Shehzad Ali | Public Health Economist | Western СŷÊÓƵ, Canada |
Paulina Gonzalez | PDRA, CI Support | Rotherham Doncaster & South Humber NHS Foundation Trust |
Jeannie Mckie | Research Governance Manager | Rotherham Doncaster & South Humber NHS Foundation Trust |
Sarah Keeble | PWP / CSO Helping with recruitment etc | Rotherham Doncaster & South Humber NHS Foundation Trust |
Jodie Keyworth | Head of Business Development | Rotherham Doncaster & South Humber NHS Foundation Trust |
Jennie Smith | Communications Officer, PPI Lead | Rotherham Doncaster & South Humber NHS Foundation Trust |
Oliver Davis | Clinical Studies Officer | Rotherham Doncaster & South Humber NHS Foundation Trust |
Funder and Sponsor
This project is funded by the National Institute for Health Research, Health Technology Assessment (NIHR HTA) Programme. The views expressed are those of the author(s) and not necessarily those of the NIHR or the Department of Health and Social Care. Rotherham, Doncaster and South Humber NHS Foundation Trust (RDaSH) are the trial sponsor.