Diana Papaioannou
BChD, MSc
School of Medicine and Population Health
Senior Research Fellow/Portfolio Lead
CTRU Deputy Director
+44 114 222 0766
Full contact details
School of Medicine and Population Health
3rd floor
The Innovation Centre
217 Portobello
Sheffield
S1 4DP
- Profile
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Diana Papaioannou is an Assistant Director of the Clinical Trials Research Unit (CTRU) and a Senior Research Fellow with expertise in trial conduct and methodology and CTIMP trials (Clinical Trials of Investigational Medicinal Products).
Diana has extensive experience in designing and implementing large multi-centre trials, particularly CTIMP trials. Since 2014, she has been co-applicant on 8 NIHR funded trials. Diana also held a Clinical Trials Unit (CTU) Efficient Trials award to develop recommendations for recording harms in behaviour change interventions. Diana was the Quality Assurance Lead for Sheffield CTRU between 2014 to 2024.
Diana is CTRU lead, providing senior CTRU oversight, for the following studies: EXPERTS-ALS (NIHR158515), MISSION-EB (NHSE/NIHR EME: 127963), PRAISE (NIHR153170) and MAP (NIHR167171).
Diana previously provided CTRU senior oversight and a co-applicant on the MAGIC trial (NIHR HTA: 16/80/08) and STAR-MS trials (NIHR EME: 16/126/26). I provided CTIMP expertise to the ASTIClite trial (NIHR EME: 15/178/09).
In 2019, Diana became Assistant Director at CTRU, responsible for the CTRU management with the CTRU Director and the CTRU management group and coordinating the CTRU
Diana joined the CTRU in May 2011 as the Trial Co-ordinator for a multi-centre randomised controlled trial, REPOSE (The Relative Effectiveness of Pumps over MDI and Structured Education for Type-1 diabetes).
Prior to joining CTRU, she worked with the ScHARR Technology Assessment Group from July 2006, as an Information Specialist and Systematic Reviewer undertaking health technology assessments for the National Institute for Health and Clinical Excellence (NICE) and the NIHR Evaluation, Trials and Studies Coordinating Centre (NETSCC).
- Research interests
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- Clinical trial design
- Clinical trials of Investigational Medicinal Products
- Adverse event recording in behavioural trials
- Systematic reviews
- Publications
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Show: Featured publications All publications
Featured publications
Books
Journal articles
Chapters
Conference proceedings papers
All publications
Books
Journal articles
Chapters
Conference proceedings papers
Reports
Posters
- Research group
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CTRU, DTS
- Grants
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Metformin and Psychosis Weight Prevention Trial (MAP Trial). NIHR HTA.
Coapplicant. £3million
EXPErimental medicine Route To Success in Amyotrophic Lateral Sclerosis
(EXPERTS-ALS) NIHR EME and NIHR BRC. Coapplicant. £4,796,266.62. Start date:
1 Sep 2023.
Recording Harms in Behavioural change Intervention Trials (RHABIT) Project. NIHR CTU support funding for Efficient trials. Principal Investigator. £79,015
MissionEB trial: Double blinded placebo control study of Mesenchymal Intravenous
Stromal cell Infusions in children with recessive dystrophic Epidermolysis Bullosa.
Coapplicant. £2,539,714. Start date Aug 2020
STAR-MS trial: Autologous Stem Cell Transplantation versus Alemtuzumab in
Relapsing Remitting MS. Coapplicant. £2,350,322. Start date Jan 2019
The MAGIC trial: Melatonin for Anxiety prior to General Anaesthesia. HTA 16/80/08,
Coapplicant.£1.65million. Dec 2017 to September 2024.
Autologous Stem Cell Transplantation In refractory Crohns disease - Low Intensity
Therapy Evaluation (ASTIC-LITE). Sep 2017 to 2021
SCRATCH trial (Induced Endometrial Trauma in IVF). HTA 14/08/05, Coapplicant.
£1.25million. Dec 2015 to Sep 2020
- Teaching interests
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I am interested in supervising research students in areas such as RCT methodology and evaluation of health technologies.