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DNA strands

Sheffield spinout takes major step towards advancing pioneering treatments for Hereditary Spastic Paraplegia (HSP)

BlackfinBio Limited is a spinout company from the СŷÊÓƵ of Sheffield set to pioneer novel therapies for rare genetic neurological diseases.

Image of motor neurones

Groundbreaking EXPERTS-ALS study for MND treatments

The EXPErimental medicine Route To Success in ALS (EXPERTS-ALS) project aims to rapidly screen potential drugs for evidence that they can slow down damage to the nervous system occurring in people with motor neuron disease
Professor Mimoun Azzouz holding a petri dish

Comment: Turning the biggest disappointment of a career into a new era for UK gene therapy manufacturing

Professor Mimoun Azzouz discusses career challenges before opening the Gene Therapy Innovation and Manufacturing Centre (GTIMC) at the СŷÊÓƵ of Sheffield.
Medical illustration of a brain with stroke symptoms

Our 2024 research highlights

As the year comes to a close, we want to take a moment to reflect on and celebrate some of our research news stories from 2024.
Nerve cells

Scientists discover how to prevent death of nerve cells in most common genetic forms of MND and dementia

Scientists have found a novel way to block the transportation of mutant RNA and subsequent production of toxic repeat proteins which lead to the death of nerve cells in the most common subtypes of MND and FTD.
Scientist undertaking experiment in lab

Rare Disease Day 2023 – research at the Neuroscience Institute

The 28th of February is globally recognised as rare disease day, a day annually devoted to raising awareness of rare diseases and what this means for millions of people living with them worldwide.